While both injectables use the same component, hyaluronic acid, Profhilo and Dermal Filler work very differently. Dermal filler is injected to enhance a specific area such as the lips and cheeks, and In this way it augments your natural facial structure to produce more angular cheekbones or plumper lips. Profhilo works very differently because it is made of hyaluronic acid, while dermal fillers have other components. Because Profhilo is made of a completely natural skin substance, it blends into the skin seamlessly and distributes itself evenly.